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751 articles
July 202624
Effectiveness and Feasibility of Interventions for Weight Management of Young Adults in Low- and Middle-Income Countries (LMICs): A Systematic Review With Meta-Analysis.
This systematic review and meta-analysis evaluated the effectiveness of weight management interventions for young adults in low- and middle-income countries (LMICs).
Comparative Efficacy of GLP-1 Receptor Agonists, Exercise, and Their Combination on Body Composition and Glucolipid Metabolism in Adults With Overweight or Obesity: A Network Meta-Analysis of Randomized Controlled Trials.
This network meta-analysis evaluated the effects of GLP-1 receptor agonists, structured exercise, and their combination on body composition and glucolipid metabolism in adults with overweight or obesity.
Tirzepatide, cardiovascular outcomes and mortality in obesity and diabetes: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the impact of tirzepatide on cardiovascular outcomes and mortality in 29,023 adults with type 2 diabetes or obesity.
Safety, tolerability, relative bioavailability, pharmacokinetics, and pharmacodynamics of single and multiple doses of the novel oral bofanglutide in healthy Chinese participants.
This randomized controlled trial assessed the safety, pharmacokinetics, and pharmacodynamics of oral bofanglutide in healthy Chinese participants.
Sustained and attenuated effects of transitioning from supervised to self-managed resistance training in older adults with type 2 diabetes and sarcopenia: a randomized controlled trial.
This randomized controlled trial investigated the effects of transitioning from supervised resistance training (SRT) to self-managed training in older adults (≥65 years) with type 2 diabetes and sarcopenia.
Renal Impairment Does Not Affect Pharmacokinetics, Safety or Tolerability of Zenagamtide.
This Phase I clinical trial evaluated the pharmacokinetics, safety, and tolerability of zenagamtide in adults with varying degrees of renal impairment compared to those with normal renal function.
Comparative Efficacy of Insulin Delivery Modalities on Glycaemic Control in Adults With Type 2 Diabetes: A Systematic Review and Network Meta-Analysis.
This systematic review and network meta-analysis compared insulin delivery modalities in adults with insulin-treated type 2 diabetes, using parallel-group randomised trials identified through searches of eight databases…
Vegan multinutrient supplementation significantly increases Omega-3 index and 25-OH-vitamin D status: a randomized, double-blind, placebo-controlled trial in healthy young vegans.
This randomized, double-blind, placebo-controlled trial evaluated the effects of multinutrient supplementation on omega-3 index and vitamin D status in 72 healthy vegan adults aged 19-57.
Premeal insulin administration lowers postprandial blood glucose and increases myocardial microvascular blood flow in people with type 1 diabetes: a randomised, crossover clinical trial.
This randomized crossover trial evaluated the effects of premeal versus postmeal insulin administration on vascular function in 18 young adults with type 1 diabetes.
Postprandial Vitamin E Plasma Enrichment and Second Meal Effect in Women with and without Metabolic Dysfunction-Associated Steatotic Liver Disease.
This randomized controlled trial examined postprandial vitamin E absorption in healthy women and those with obesity and metabolic dysfunction-associated steatotic liver disease (MASLD).
Neurofeedback intervention based on functional near-infrared spectroscopy compared with sham control to improve inhibitory cognitive control in patients with severe obesity and food addiction: The protocol of a monocentric prospective randomized parallel-group single-blind interventional study.
This randomized controlled trial investigates the efficacy of functional near-infrared spectroscopy (fNIRS)-based neurofeedback in enhancing inhibitory cognitive control among 50 females with severe obesity and food…
How Families Influence Self-Management Among the Role of Family to Patients With Type 2 Diabetes? A Systematic Review and Meta-Synthesis.
This systematic review and meta-synthesis examined qualitative and mixed-methods research on how families influence self-management among people with type 2 diabetes.
Combination Therapy of GLP-1 RA and SGLT2i in Patients with Established Heart Failure: A Systematic Review and Meta-Analysis of Observational Studies.
This systematic review and meta-analysis evaluated the effects of combination therapy with GLP-1 RA and SGLT2i compared to SGLT2i alone in patients with established heart failure.
Insertion of Subdermal Hormonal Implant May Trigger Complex Regional Pain Syndrome: A Case Report.
An adolescent female developed complex regional pain syndrome (CRPS) in her upper extremity following the routine insertion of a subdermal contraceptive implant.
Effects of intensive lifestyle interventions with calorie-carbohydrate-restricted diet versus time-restricted eating on appetite and binge eating in type 2 diabetes: A randomized controlled trial.
This randomized controlled trial assessed the effects of intensive lifestyle interventions, specifically calorie-carbohydrate restriction (CCR) and time-restricted eating with CCR (TRE + CCR), on appetite and binge…
Efficacy and Safety of Anti-Obesity Medications for Weight Loss Maintenance in Adults With Overweight or Obesity: A Systematic Review and Meta-Analysis of Randomised Controlled Trials.
This systematic review and meta-analysis evaluated the efficacy and safety of anti-obesity medications (AOMs) for weight maintenance in adults with overweight or obesity.
Pre-exercise meal macronutrient composition and acute inflammatory response in males with type 2 diabetes mellitus.
This randomized controlled trial investigated the effect of pre-exercise meal macronutrient composition on the acute inflammatory response in ten males with well-controlled type 2 diabetes mellitus (T2DM).
Meta-analysis of sodium glucose transport 2 inhibitors versus other glucose-lowering agents on the progression of diabetic retinopathy and diabetic macular edema.
This meta-analysis evaluated the effects of sodium-glucose cotransporter-2 inhibitors (SGLT2i) on diabetic retinopathy (DR) and diabetic macular edema (DME) progression in a population of 1,785,409 patients.
Exercise training for executive function in type 2 diabetes: A systematic review and practice implications.
This systematic review assessed exercise interventions lasting at least four weeks and executive-function outcomes in people with type 2 diabetes.
Prevalence and types of insulin-pump-related skin complications in children and adolescents with type 1 diabetes: A systematic review and meta-analysis.
This systematic review and meta-analysis examined the prevalence and types of insulin-pump-related skin complications in children and adolescents with type 1 diabetes.
Sodium zirconium cyclosilicate compared with potassium restriction for hyperkalemia management in type 2 diabetes: The SILVERSTAR trial.
The SILVERSTAR trial evaluated the noninferiority of sodium zirconium cyclosilicate versus a potassium-restricted diet for managing hyperkalemia in individuals with type 2 diabetes.
Environmental Toxicants and Polycystic Ovary Syndrome: Implications for a Metabolic-Ovarian Framework (PMOS) - A Systematic Review.
This systematic review evaluated the association between exposure to potentially toxic elements and endocrine disruptors in women with polycystic ovary syndrome (PCOS).
Pharmacokinetics, Pharmacodynamics, and Safety of Once-Weekly Insulin Efsitora Alfa in Chinese Patients with Type 2 Diabetes: A Phase 1 Open-Label, Randomized, Active-Controlled Trial.
This phase 1 randomized controlled trial evaluated the pharmacokinetics, pharmacodynamics, and safety of once-weekly insulin efsitora alfa compared to once-daily insulin glargine in Chinese patients with type 2…
Efficacy and Safety of SGLT2 Inhibitors and GLP-1 Receptor Agonists on Ventricular Arrhythmias and Cardiovascular Events: A Disease-Stratified Network Meta-Analysis.
This disease-stratified network meta-analysis compared SGLT2 inhibitors and GLP-1 receptor agonists for ventricular arrhythmias and cardiovascular outcomes in people with type 2 diabetes, heart failure, or both.
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