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1064 articles

July 202624

Clinical ResearchPsychiatryOpen access

Effects of a brief primary care intervention for post-traumatic stress disorder symptoms after critical illness on health-related quality of life - A secondary analysis of the PICTURE randomised controlled trial.

This secondary analysis of the PICTURE randomised controlled trial evaluated the impact of a brief GP-delivered narrative exposure intervention on health-related quality of life (HRQoL) in 319 adult ICU survivors with…

Eur J Gen PractJul 21, 2026Read summary
Clinical ResearchPsychiatryOpen access

Integrated exposure-based therapy for co-occurring post-traumatic stress and substance use among young people: a randomized controlled trial.

This randomized controlled trial evaluated the efficacy of the integrated exposure-based treatment COPE-A for post-traumatic stress disorder (PTSD) and substance use disorder (SUD) in young people aged 12-25.

Eur J PsychotraumatolJul 21, 2026Read summary
Clinical ResearchPsychiatry

Neural signatures of stress resilience in emotion and cognitive domains: A meta-analysis of task-based fMRI studies.

This meta-analysis examined neural correlates of stress resilience in 1373 trauma-exposed individuals, revealing distinct patterns in emotion and cognitive domains.

Neurosci Biobehav RevJul 21, 2026Read summary
Clinical ResearchPsychiatry

Pharmacogenomics of antipsychotic-induced weight gain: A systematic review.

This systematic review examined the pharmacogenomics of antipsychotic-induced weight gain (AIWG) by analyzing 53 studies. It identified consistently replicated genes such as DRD2, HTR2C, and MC4R, along with novel…

Schizophr ResJul 21, 2026Read summary
Clinical ResearchPsychiatry

Prevalence of psychosis in South Asia: A systematic review and meta-analysis.

This systematic review and meta-analysis assessed the prevalence of psychosis in South Asia, analyzing data from 31 studies across five countries.

Schizophr ResJul 21, 2026Read summary
Clinical ResearchPediatrics

The impact of different types of play interventions on anxiety and depressive symptoms in children with cancer: A systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the effects of play interventions on anxiety and depressive symptoms in 1541 children with cancer.

J Pediatr NursJul 21, 2026Read summary
Clinical ResearchPreventive Medicine / Public Health

Implementation factors shaping British Columbia's drug decriminalization pilot: A systematic review with narrative synthesis.

This systematic review examined the implementation of British Columbia's drug decriminalization pilot, which began in January 2023.

Int J Drug PolicyJul 21, 2026Read summary
Clinical ResearchNeurologyOpen access

Structural Neuroimaging Alterations in Primary Burning Mouth Syndrome: A Seed-Based d Mapping (SDM-PSI) Meta-Analysis.

This meta-analysis examined structural neuroimaging alterations in 59 patients with primary burning mouth syndrome (pBMS) compared to 63 healthy controls.

Int Dent JJul 21, 2026Read summary
Clinical ResearchPediatrics

Prenatal opioid exposure, and health, social and educational outcomes for school-aged children: A systematic review.

This systematic review examined the impact of prenatal opioid exposure (POE) on health, social, and educational outcomes in children aged 5-18 years.

AddictionJul 21, 2026Read summary
Clinical ResearchPsychiatryOpen access

Evidence for pro-cognitive benefits of cannabinoids in people with bipolar disorder.

This randomized controlled trial examined the effects of cannabis use on cognitive functions in individuals with bipolar disorder (BD) and healthy controls.

NeuropsychopharmacologyJul 21, 2026Read summary
Clinical ResearchPsychiatryOpen access

Optimizing Expectations Leads to Enhanced Efficacy of a Mindfulness-Based Intervention in Individuals With Low-Baseline Expectations: A Randomized Controlled Trial.

This randomized controlled trial investigated the impact of optimizing treatment expectations on the efficacy of a mindfulness intervention in 66 healthy participants.

J Clin PsycholJul 21, 2026Read summary
Clinical ResearchPsychiatry

Targeting depression before it starts: An updated systematic review and meta-analysis of preventive interventions in young adults from randomized controlled trials.

This systematic review and meta-analysis evaluated the effectiveness of psychosocial preventive interventions for major depressive disorder (MDD) in young adults aged 18-25.

J Affect DisordJul 20, 2026Read summary
Clinical ResearchGeriatrics

Artificial intelligence enabled social robotic interventions (PARO) in Australian dementia care: A systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the effectiveness of PARO-based socially assistive robotic interventions in reducing behavioral and psychological symptoms in dementia patients within Australian…

Int J Med InformJul 20, 2026Read summary
Clinical ResearchGeriatrics

Association between salivary oxytocin concentration and social loneliness in older adults: Findings from an uncontrolled pre-post multimodal intervention study.

This uncontrolled pre-post multimodal intervention study examined the relationship between salivary oxytocin levels and social loneliness in 62 older adults (average age 60+) in Spain.

PsychoneuroendocrinologyJul 20, 2026Read summary
Clinical ResearchPsychiatryOpen access

The effect of monetary versus point-based rewards on effort-cost decision making in individuals at clinical high risk for psychosis.

This randomized controlled trial examined the effects of monetary versus point-based rewards on effort-cost decision-making in individuals at clinical high risk for psychosis (CHR) and healthy controls.

Schizophr ResJul 20, 2026Read summary
Clinical ResearchGeriatrics

Intelligent assistive technology for people with dementia: A meta-analysis.

This meta-analysis evaluated the effectiveness of intelligent assistive technology (IAT) in improving the quality of life for individuals with dementia, analyzing data from 12 studies involving 732 participants.

Geriatr NursJul 20, 2026Read summary
Clinical ResearchNeurologyOpen access

A systematic review of neuroimaging studies of adults aged 35 and older with clinical, symptomatic and genetic risk for attention-deficit/hyperactivity disorder.

This systematic review examined neuroimaging studies of adults aged 35 and older with clinical, symptomatic, or genetic risk for ADHD.

Dialogues Clin NeurosciJul 19, 2026Read summary
Clinical ResearchPsychiatry

Combination pharmacotherapy in psychotic depression: A systematic review and pairwise meta-analysis of randomized trials.

This systematic review and pairwise meta-analysis evaluated the efficacy of combination pharmacotherapy in treating psychotic depression.

J Affect DisordJul 18, 2026Read summary
Clinical ResearchPsychiatry

Resting magnetoencephalography alterations in severe mental illnesses: A systematic review.

This systematic review examined resting-state magnetoencephalography (MEG) findings in schizophrenia, major depressive disorder (MDD), and bipolar disorder.

Neurosci Biobehav RevJul 18, 2026Read summary
Clinical ResearchPsychiatry

Continuous theta-burst stimulation over the right DLPFC modulates central executive network connectivity in depression: exploratory analysis of a randomized clinical trial.

This randomized controlled trial explored the effects of continuous theta-burst stimulation (cTBS) over the right dorsolateral prefrontal cortex (DLPFC) on functional connectivity in 70 patients with major depressive…

J Affect DisordJul 17, 2026Read summary
Clinical ResearchPsychiatryOpen access

Alliance Ruptures and Psychotherapy Outcomes: A Multilevel Meta-Analysis of Their Association.

This meta-analysis examined the relationship between alliance ruptures and psychotherapy outcomes, analyzing data from 301 clients across four studies.

J Clin PsycholJul 17, 2026Read summary
Clinical ResearchPsychiatry

Cardiovascular risks in psychiatric disorders and psychiatric risks in cardiovascular disorders: implications for prevention and clinical management - a large-scale umbrella review encompassing 76 meta-analyses.

This umbrella review analyzed 76 meta-analyses to explore the co-occurrence of psychiatric and cardiovascular disorders. It found that 91.7% of prevalence estimates met moderate to strong credibility criteria.

J Psychosom ResJul 17, 2026Read summary
Clinical ResearchPsychiatry

A randomized trial of omega-3 fatty acids plus inositol versus N-acetylcysteine for the treatment of depression and mania in emotionally dysregulated youth age 5-17 with and without autism traits.

This randomized controlled trial evaluated the effectiveness of omega-3 fatty acids plus inositol (O3I) versus N-acetylcysteine (NAC) in treating depression and mania in youth aged 5-17 with emotional dysregulation…

J Affect DisordJul 16, 2026Read summary
Clinical ResearchPsychiatry

Examining early-phase symptom trajectories in interpersonal psychotherapy versus antidepressant medication for adults with depression: A dynamic time warp network analysis.

This randomized controlled trial examined symptom trajectories in adults with depression undergoing either interpersonal psychotherapy (IPT) or selective serotonin reuptake inhibitors (SSRIs) over six weeks.

J Affect DisordJul 16, 2026Read summary

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