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360 articles

September 202624

Clinical ResearchNeurology

Systolic blood pressure targets after successful endovascular thrombectomy: a network meta-analysis of randomized controlled trials.

This network meta-analysis evaluated the impact of different systolic blood pressure (SBP) targets on outcomes after endovascular thrombectomy in eight studies.

Neurol SciSep 29, 2026Read summary
Clinical ResearchEmergency Medicine

Efficacy of a needle-free blood collection device (PIVO Pro) for avoiding contaminated blood culture sets in Australian emergency departments: protocol for an adaptive group sequential randomised controlled trial.

This study protocol outlines a multicentre, adaptive group sequential randomised controlled trial aimed at evaluating the efficacy of the needle-free blood collection device, PIVO Pro, in reducing blood culture…

BMJ OpenSep 28, 2026Read summary
Case ReportCardiologyOpen access

Extracorporeal cardiopulmonary resuscitation for cardiogenic shock in a Jehovah's witness.

A Jehovah's Witness patient in cardiogenic shock underwent successful resuscitation using veno-arterial extracorporeal membrane oxygenation (ECMO) without the need for blood transfusions.

J Artif OrgansSep 28, 2026Read case
Clinical ResearchNeurologyOpen access

Intravenous thrombolysis use before interhospital transfer for thrombectomy: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the impact of intravenous thrombolysis (IVT) before interhospital transfer for endovascular thrombectomy (EVT) in patients with large-vessel occlusion acute ischemic…

J NeurolSep 28, 2026Read summary
Clinical ResearchNeurologyOpen access

Endovascular Treatment for Patients Aged ≥80 Years with Large Ischemic Stroke.

This randomized controlled trial evaluated the effectiveness and safety of endovascular treatment (EVT) in patients aged ≥80 years with large ischemic stroke.

Clin Interv AgingSep 28, 2026Read summary
Case ReportGeriatrics

Electrical Impedance Tomography-Guided Precision Nursing in an Older Patient With Septic Shock and ARDS: A Case Report.

A 79-year-old patient with septic shock, ARDS, and MODS underwent precision nursing management utilizing electrical impedance tomography (EIT).

Nurs Crit CareSep 26, 2026Read case
Case ReportOphthalmology

Clinical Reasoning: An Immunocompetent Young Adult With Acute Vision Loss.

A 23-year-old male presented with worsening headaches, bilateral retrobulbar pain, and blurred vision. Evaluation indicated bilateral optic neuritis, with MRI, CSF analysis, and blood tests showing normal results except…

NeurologySep 25, 2026Read case
Case ReportGeneral Surgery

Migration of an ingested orthodontic retainer into the psoas muscle presenting with radiculopathy-like symptoms: A case report.

A 26-year-old man presented with abdominal pain after swallowing an orthodontic retainer. Although his abdominal pain improved, he later experienced persistent right lower-limb paresthesia and pain.

Medicine (Baltimore)Sep 25, 2026Read case
Clinical ResearchEmergency Medicine

Intraosseous versus intravenous access in adult out-of-hospital cardiac arrest: a Bayesian secondary analysis of the PARAMEDIC-3 randomised controlled trial.

This pre-planned Bayesian secondary analysis of the PARAMEDIC-3 randomised controlled trial compared intraosseous-first with intravenous-first vascular access in adults with out-of-hospital cardiac arrest requiring…

ResuscitationSep 25, 2026Read summary
Clinical ResearchEmergency Medicine

AI Decision Support for Emergency Triage of Large Vessel Occlusion Using Noncontrast Computed Tomography: Systematic Review and Bayesian Diagnostic Test Accuracy Network Meta-Analysis.

This systematic review and Bayesian network meta-analysis evaluated the diagnostic accuracy of noncontrast computed tomography (NCCT)-based AI for detecting anterior circulation large vessel occlusion (LVO) compared to…

J Med Internet ResSep 24, 2026Read summary
Clinical ResearchInternal Medicine (General)

Clinical Surveillance Technologies in Nonintensive Care Unit Hospital Settings: Systematic Review and Bayesian Network Meta-Analysis of Randomized Trials.

This systematic review and Bayesian network meta-analysis evaluated the clinical effects of rule-based electronic surveillance (RB-ES), predictive model-based electronic surveillance (PM-ES), and continuous physiologic…

J Med Internet ResSep 24, 2026Read summary
Clinical ResearchEmergency MedicineOpen access

From dental adhesives to injectable hemostats: a scoping review of antimicrobial biomaterials for oral soft-tissue bleeding.

This scoping review examines antimicrobial biomaterials for managing oral soft-tissue bleeding, focusing on injectable materials that provide rapid hemostasis and antimicrobial protection.

BMC Oral HealthSep 23, 2026Read summary
Clinical ResearchGastroenterologyOpen access

Is ultra-early endoscopy always beneficial? A systematic review and meta-analysis of timing-dependent outcomes in nonvariceal upper gastrointestinal bleeding.

This systematic review and meta-analysis evaluated the impact of ultra-early endoscopy (≤6 hours) versus early endoscopy (>6 hours) on clinical outcomes in adults with nonvariceal upper gastrointestinal bleeding…

PeerJSep 23, 2026Read summary
Case ReportEmergency Medicine

An 18-Year-Old Woman with Abdominal Pain.

An 18-year-old woman presented to the emergency department with acute abdominal pain. Through a systematic approach involving questions, physical examination, and diagnostic testing, the clinical team refined their…

NEJM EvidSep 22, 2026Read case
Case ReportUrology

Testicular torsion after prior orchiopexy in an older adult: diagnostic pitfalls and the importance of multipoint fixation.

A man in his 60s presented with acute scrotal pain on two occasions, having a history of bilateral orchiopexy due to prior testicular torsion. Despite previous surgeries, recurrent torsion was diagnosed.

BMJ Case RepSep 22, 2026Read case
Case ReportNeurologyOpen access

Multiple organ failure following severe heat stroke complicated by AMSAN-type Guillain-Barré syndrome: a case report and literature review.

A 57-year-old man developed confusion and hyperthermia while hiking, leading to a diagnosis of severe heat stroke and subsequent multiple organ failure.

BMC NeurolSep 22, 2026Read case
Case ReportEmergency Medicine

Large vessel occlusion stroke in venom-induced consumption coagulopathy after viper envenomation.

A woman in her mid-60s presented with left-sided hemiplegia 6 hours post-viper bite. Investigations revealed profound venom-induced consumption coagulopathy and an acute right middle cerebral artery occlusion.

BMJ Case RepSep 21, 2026Read case
Clinical ResearchNeurology

Effect of periprocedural antithrombotic medication on functional outcome and symptomatic intracranial hemorrhage in patients with carotid tandem lesions.

This post-hoc analysis of the MR CLEAN-MED randomized controlled trial evaluated the impact of periprocedural antithrombotic medication on functional outcomes and symptomatic intracranial hemorrhage in 100 patients with…

BMJ OpenSep 21, 2026Read summary
Case ReportEmergency Medicine

Oxygen desaturation in patients with functional seizures: pitfalls for the unwary.

A patient with recurrent functional seizures exhibited documented oxygen desaturation, leading to extensive cardiopulmonary investigations and repeat video-electroencephalogram evaluation.

Pract NeurolSep 20, 2026Read case
Clinical ResearchNeurologyOpen access

Safety and efficacy of repeated intravenous thrombolysis within 3 months for acute ischemic stroke: a systematic review and individual-patient data meta-analysis.

This systematic review and individual-patient data meta-analysis evaluated the safety and efficacy of repeated intravenous thrombolysis (RIVT) for acute ischemic stroke (AIS) within 90 days of a previous treatment.

J NeurolSep 19, 2026Read summary
Clinical ResearchInternal Medicine (General)

Applications of the Early Warning Score as an outcome measure: a systematic review of methodologies.

This systematic review evaluated the use of Early Warning Scores (EWS) as outcome measures in interventional and comparative studies.

BMJ Health Care InformSep 18, 2026Read summary
Clinical ResearchEmergency Medicine

Sex-based and gender-based details in accelerated diagnostic protocol implementation among emergency department patients presenting with chest pain: a systematic review.

This systematic review evaluated the incorporation of sex and gender factors in accelerated diagnostic protocols (ADPs) for chest pain in emergency departments.

Emerg Med JSep 18, 2026Read summary
Clinical ResearchEmergency Medicine

On the optimal sodium correction rate in hyponatraemia and clinical outcome: a meta-analysis.

This meta-analysis examined the impact of sodium correction rates on mortality in patients with hyponatraemia, analyzing 11 studies with 27,672 cases.

Emerg Med JSep 18, 2026Read summary
Clinical ResearchPediatrics

Point-of-care decision rule for antibiotic prescriptions in young children with fever without source: an open cluster randomised trial.

This open cluster randomised trial evaluated a point-of-care decision rule aimed at reducing antibiotic prescriptions in children aged 6 days to 36 months with fever without source across 25 European emergency…

Arch Dis ChildSep 18, 2026Read summary

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