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1064 articles

June 20268

Clinical ResearchPsychiatryOpen access

Predicting Change in Brief Treatment for BPD: The Role of Defensive Functioning and Pervasiveness in Relationship Patterns.

This randomized controlled trial investigated the role of defensive functioning and core conflictual relationship themes (CCRT) in predicting symptom change in 60 patients with borderline personality disorder (BPD)…

J Clin PsycholJun 2, 2026Read summary
Clinical ResearchGeriatricsOpen access

Interventions to Reduce Loneliness in Informal Caregivers of People With Dementia: A Systematic Review.

This systematic review evaluated interventions aimed at reducing loneliness in informal caregivers of dementia patients. Eight studies were analyzed, with three being randomized controlled trials.

J Clin NursJun 2, 2026Read summary
Clinical ResearchNeurology

"A Better Way of Just Being Free": Exploring How Stroke Survivors With Aphasia Experienced an Intervention Combining Communication Strategy Training With Acceptance and Commitment Therapy.

This Phase I clinical trial reported qualitative findings from posttreatment interviews with 14 stroke survivors with aphasia who received a refined intervention combining Acceptance and Commitment Therapy (ACT) with…

Am J Speech Lang PatholJun 2, 2026Read summary
Clinical ResearchPsychiatry

Depression stigma, treatment-seeking intentions, and barriers to care among adolescents: demographic factors in a crowdsourced sample.

This clinical trial investigated the impact of age, gender, and race/ethnicity on depression stigma, barriers to care, and treatment-seeking intentions among 1127 US adolescents aged 14-18.

Psychiatry ResJun 1, 2026Read summary
Case ReportNeurology

Successful treatment of abnormal sensation associated with restless legs syndrome in adrenoleukodystrophy using Gunggwijohyeoleum-Jeilgagam: A case report.

A 50-year-old man with adrenoleukodystrophy (ALD) and a 10-year history of refractory restless legs syndrome (RLS) presented with severe symptoms, including insomnia and gait impairment.

Explore (NY)Jun 1, 2026Read case
Clinical ResearchPsychiatry

The effect of treatments for postpartum depression on breastfeeding practices: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the impact of treatments for postpartum depression (PPD) on breastfeeding practices among affected mothers.

MidwiferyJun 1, 2026Read summary
Clinical ResearchPsychiatry

Repetitive Transcranial Magnetic Stimulation (rTMS) for Adolescent Depression: A Systematic Review and Meta-Analysis of Treatment Response and Suicidal Ideation Reduction.

This systematic review and meta-analysis evaluated the efficacy and safety of repetitive transcranial magnetic stimulation (rTMS) for treating major depressive disorder in adolescents.

Acta Psychiatr ScandJun 1, 2026Read summary
Clinical ResearchPsychiatry

Systemic oxidative stress in children and adolescents with attention deficit hyperactivity disorder: a meta-analysis of oxidative and antioxidant biomarkers.

This meta-analysis examined oxidative stress and antioxidant biomarkers in 1,325 children and adolescents with ADHD compared to 1,272 healthy controls.

Brain Behav ImmunJun 1, 2026Read summary

May 202616

Clinical ResearchGeriatrics

Mental Health Stereotypes and Aging: Effects on Mood and Decision Making.

This randomized controlled trial examined the impact of negative aging stereotypes on the mood, risk tolerance, and patience of older adults (mean age = 68.9).

Exp Aging ResMay 31, 2026Read summary
Clinical ResearchPsychiatry

Credibility and expectancy associated with ultra-brief and standard-length digital treatments: A preliminary examination of impact on treatment outcome.

This secondary analysis of a randomized controlled trial examined whether treatment credibility and outcome expectancy differed between ultra-brief and standard-length digital cognitive behavioural transdiagnostic…

Br J Clin PsycholMay 31, 2026Read summary
Clinical ResearchPsychiatry

Symptom profiles at baseline are associated with remission in major depression: a confirmatory analysis of the PANDORA trial.

This randomized controlled trial analyzed 215 adults with Major Depressive Disorder (MDD) from the PANDORA trial to assess the relationship between baseline depressive symptom profiles and remission.

J Psychiatr ResMay 30, 2026Read summary
Clinical ResearchPsychiatry

Pharmacological and non-pharmacological treatments for chronic insomnia in perimenopausal and postmenopausal women: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated pharmacological and non-pharmacological treatments for chronic insomnia in perimenopausal and postmenopausal women.

Sleep MedMay 30, 2026Read summary
Clinical ResearchPsychiatryOpen access

Safety and tolerance of oral ketamine: A systematic review.

This systematic review assessed the safety and tolerability of oral ketamine across various clinical populations, including adults and children.

Psychiatry Clin NeurosciMay 30, 2026Read summary
Clinical ResearchEndocrinology

Prevalence and outcomes of co-occurring psychiatric and endocrine, metabolic, and nutritional disorders: An atlas based on umbrella review of 254,154,533 records.

This meta-analysis reviewed 81 studies involving over 254 million records to assess the prevalence and outcomes of co-occurring psychiatric and endocrine, metabolic, and nutritional disorders.

Eur NeuropsychopharmacolMay 30, 2026Read summary
Case ReportPsychiatry

Valproate-induced acute necrotising pancreatitis in a young woman with bipolar disorder: Sustained remission after switch to lithium.

A young woman with bipolar disorder on valproate developed acute necrotising pancreatitis. Following prompt discontinuation of the medication and conservative management, her condition improved.

Trop DoctMay 30, 2026Read case
Clinical ResearchPsychiatry

Probing motivation in internalizing symptoms: A systematic review of the effort expenditure for rewards task (EEfRT).

This systematic review examined the Effort Expenditure for Rewards Task (EEfRT) across 46 studies involving clinical samples with internalizing disorders.

J Behav Ther Exp PsychiatryMay 29, 2026Read summary
Clinical ResearchPsychiatryOpen access

Post-traumatic stress disorder moderates the association between BrainAge acceleration and GrimAge acceleration.

This meta-analysis investigated the role of post-traumatic stress disorder (PTSD) in moderating the relationship between epigenetic aging (GrimAge) and brain aging in 312 individuals, including 174 with PTSD.

Neurobiol AgingMay 29, 2026Read summary
Clinical ResearchPsychiatry

The impact of accelerated 40 Hz transcranial alternating current stimulation on sleep in patients with major depressive disorder: A secondary analysis of a randomized controlled trial.

This secondary analysis of a randomized controlled trial evaluated the effects of accelerated 40 Hz transcranial alternating current stimulation (tACS) on sleep in patients with major depressive disorder (MDD).

J Affect DisordMay 29, 2026Read summary
Clinical ResearchPsychiatry

Risk factors for suicidal behaviour in people with dementia: A systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the risk factors for suicidal behavior in people with dementia (PwD). It found that PwD have a 62% increased risk of suicidal behavior compared to non-dementia controls…

J Affect DisordMay 29, 2026Read summary
Clinical ResearchGeriatrics

Cannabinoids Treatment for Agitation in Alzheimer's Disease: A Systematic Review and Meta-Analysis With Bayesian and Sequential Trial Analyses.

This systematic review and meta-analysis evaluated the efficacy and safety of cannabinoid-based therapies for agitation in Alzheimer's disease, involving 221 participants across seven studies.

Am J Geriatr PsychiatryMay 29, 2026Read summary
Clinical ResearchNeurology

Beyond seizures: eye tracking evidence of cognitive dysfunction in epilepsy - A systematic review.

This systematic review examined the relationship between eye tracking metrics and cognitive dysfunction in adults with epilepsy.

Epilepsy BehavMay 29, 2026Read summary
Clinical ResearchOncology (Medical)

The Use of Ketamine for Depression in Cancer Patients: A Systematic Review of Efficacy, Safety, and Clinical Applications.

This systematic review evaluated the efficacy and safety of ketamine for treating depression in adult cancer patients. Analyzing 14 studies, it found that ketamine can provide rapid relief from depressive symptoms…

J Pain Palliat Care PharmacotherMay 29, 2026Read summary
Clinical ResearchPsychiatryOpen access

Psychedelic-induced hypomania and mania: a systematic review and meta-analysis.

This systematic review and meta-analysis examined the risk of hypomania and mania following exposure to serotonergic psychedelics in various populations.

Mol PsychiatryMay 29, 2026Read summary
Clinical ResearchPsychiatry

Adjunctive intermittent theta-burst stimulation for first-episode schizophrenia: A randomized clinical trial.

This randomized controlled trial evaluated the efficacy of adjunctive intermittent theta-burst stimulation (iTBS) in 100 first-episode schizophrenia patients receiving risperidone and cognitive behavioral therapy (CBT).

Psychiatry ResMay 28, 2026Read summary

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