Trending archive
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441 articles
September 20267
Prevalence of Benzodiazepine, Z-Drug and Melatonin Use in Australian Residential Aged Care Facilities: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis examined the prevalence of benzodiazepine, Z-drug, and melatonin use in Australian residential aged care facilities, analyzing data from 52 studies involving 658,585 residents.
Digital Health Interventions to Improve Medication Adherence Among Older Adults: A Systematic Review.
This systematic review evaluated the impact of digital health interventions (DHIs) on medication adherence in older adults (aged 65 and above).
Blood pressure parameters and cognitive decline and dementia after stroke or transient ischemic attack: results from the PROGRESS trial.
This randomized controlled trial analyzed blood pressure parameters in 5128 participants with stroke or transient ischemic attack from the PROGRESS trial.
Improvement in Delusional Jealousy and Caregiver Distress After Switching From Oral Galantamine to a Donepezil Transdermal Patch in Alzheimer's Disease: A Case Report.
A woman in her 60s with probable Alzheimer's disease experienced caregiver-reported delusional jealousy and marital conflicts while on oral galantamine.
The effect of vortioxetine on cognitive function in older adults with major depressive disorder: A systematic review.
This systematic review evaluated the effects of vortioxetine on cognitive function and depressive symptoms in older adults (≥65 years) with major depressive disorder.
Plasma Biomarker Effects of Oral Valiltramiprosate/ALZ-801 in Early Alzheimer's Disease from Phase 3 and Phase 2 Trials: Analysis of Core Biomarkers and Correlations with Clinical and Neuroimaging Outcomes.
This study analyzed plasma biomarkers in APOE4 homozygotes with early Alzheimer's disease from Phase 3 and Phase 2 trials of valiltramiprosate/ALZ-801.
Biological Pathways of Strength Preservation During Calorie Restriction-Induced Weight Loss Among Adults Without Obesity.
This randomized controlled trial analyzed the CALERIE study to identify molecular predictors of strength preservation during calorie restriction in healthy adults without obesity.
August 202617
Effects of strength and balance training on the structure of the aging brain.
This randomized controlled trial examined the effects of three months of strength and balance training on brain structure in 60 elderly adults aged 64-82.
Digital Acro-osteolysis Revealing Hajdu-Cheney Syndrome in an Elderly Patient: A Case Report.
An 85-year-old woman presented with infectious dactylitis of the right third finger. Radiographic examination revealed distal osteolysis in multiple digits.
Glycemic and safety outcomes of the insulin-only bionic pancreas in older adults and individuals with impaired awareness of Hypoglycemia: a post hoc analysis of a randomized pivotal trial.
This post hoc analysis of a randomized controlled trial evaluated the efficacy and safety of the iLet Bionic Pancreas in 96 older adults and individuals with impaired awareness of hypoglycemia.
Bivalent RSV Prefusion F Vaccine to Prevent Hospitalizations in Adults.
This randomized controlled trial evaluated the bivalent RSV prefusion F (RSVpreF) vaccine's effectiveness in preventing RSV-related hospitalizations among adults in Denmark and Spain.
Durability of RSV Prefusion F Vaccine Protection across Two RSV Seasons.
This randomized controlled trial evaluated the durability of protection from the RSV prefusion F vaccine (RSVpreF) in adults aged 60 and older across two RSV seasons.
Acute water ingestion influences lean soft tissue estimation from dual-energy x-ray absorptiometry: Implications for clinical diagnosis.
This randomized controlled trial investigated the effects of acute water ingestion (AWI) on dual-energy X-ray absorptiometry (DXA) estimates of lean soft tissue (LST) in 46 participants.
Atorvastatin, Cardiovascular Events, and Disability-free Survival in Older Adults.
This randomized controlled trial evaluated the effects of atorvastatin on cardiovascular events and disability-free survival in 9971 community-dwelling adults aged 70 and older without prior cardiovascular disease.
Multistrain probiotics modulate tau pathology and preserve visuospatial cognition in early cognitive impairment: A double-blind, randomized, placebo-controlled trial.
This randomized, double-blind, placebo-controlled trial investigated the effects of a multistrain probiotic supplement on plasma biomarkers and cognitive function in 87 older adults with early cognitive impairment.
Effects of eccentric overload training on lower-limb muscle strength, gait performance, balance, and explosive power in older adults: A systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the effects of eccentric overload training (EOT) on lower-limb muscle strength, gait performance, balance, and explosive power in older adults.
Clinical frailty scale for risk stratification in elderly patients with heart failure: a meta-analysis.
This meta-analysis evaluated the prognostic value of the Clinical Frailty Scale (CFS) in 2,682 elderly patients with heart failure (mean age 81.2 years).
Life-course socioeconomic position and cardiovascular diseases among older adults in low- and middle-income countries: A systematic review.
This systematic review examined the relationship between life-course socioeconomic position (SEP) and cardiovascular diseases (CVD) among older adults in low- and middle-income countries (LMICs).
Older adults with resectable gastric cancer undergoing perioperative chemotherapy or preoperative chemoradiotherapy plus perioperative chemotherapy: A secondary analysis of the AGITG TOPGEAR phase III trial.
This secondary analysis of the AGITG TOPGEAR phase III trial evaluated older adults (≥70 years) with resectable gastric cancer undergoing perioperative chemotherapy or chemoradiotherapy.
Counteracting vascular ageing with Traditional Chinese Medicine: Mechanisms at the cellular and molecular levels.
This systematic review synthesised research on how Traditional Chinese Medicine (TCM) interventions may affect vascular ageing, covering molecular mechanisms, relevant cell types and clinical studies.
Optimal dose and exercise modality to improve HbA1c in older adults with type 2 diabetes mellitus: a systematic review with pairwise, network, and dose-response meta-analyses.
This systematic review and meta-analysis evaluated the effects of various exercise modalities on HbA1c levels in older adults with type 2 diabetes mellitus.
Quadriceps muscle behavior assessed by ultrasound in septic patients: A systematic review.
This systematic review examined the use of ultrasound to assess quadriceps muscle atrophy in adults with sepsis or septic shock in ICUs.
Geriatric Assessment and Cancer Survival Prediction by the Vulnerable Elders Survey-13 Screening Tool: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the Vulnerable Elders Survey-13 (VES-13) tool's diagnostic and prognostic value in cancer patients aged 65 and older.
Effects of Resistance Training on Executive Functions in Community-Dwelling Older Adults: A Meta-Analysis.
This meta-analysis evaluated the impact of resistance training (RT) on executive functions in community-dwelling older adults without cognitive impairment.
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