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1064 articles

June 202624

Clinical ResearchPsychiatryOpen access

Transdiagnostic mapping of common and specific regional homogeneity alterations across affective and psychotic disorders.

This meta-analysis examined resting-state functional MRI studies to identify regional homogeneity (ReHo) alterations in major depressive disorder (MDD), bipolar disorder (BD), and schizophrenia (SZ).

NeuropsychopharmacologyJun 25, 2026Read summary
Clinical ResearchPsychiatry

Psychological mediators of the associations between adverse and benevolent childhood experiences and posttraumatic stress disorder (PTSD) and complex PTSD: A systematic review and meta-analysis.

This systematic review and meta-analysis examined the psychological mediators linking adverse and benevolent childhood experiences (ACEs and BCEs) to posttraumatic stress disorder (PTSD) and complex PTSD (CPTSD) in…

J Trauma StressJun 25, 2026Read summary
Clinical ResearchPsychiatry

Mapping the association between cognitive disengagement syndrome and internalizing disorders: A systematic scoping review with meta-analysis and meta-regression.

This systematic scoping review and meta-analysis examined the relationship between Cognitive Disengagement Syndrome (CDS) and internalizing disorders across 82 studies.

J Affect DisordJun 24, 2026Read summary
Clinical ResearchNeurology

Neurofeedback of somatosensory alpha oscillations modulates sensory and affective pain through dissociable neurocognitive pathways.

This randomized controlled trial investigated the effects of neurofeedback targeting somatosensory alpha oscillations on pain modulation in 80 healthy participants experiencing capsaicin-induced pain.

PainJun 24, 2026Read summary
Clinical ResearchPsychiatry

Impact of physical exercise interventions on post-traumatic stress disorder symptoms: A systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the impact of physical exercise interventions on PTSD symptoms across various populations.

Complement Ther MedJun 24, 2026Read summary
Clinical ResearchPediatrics

Efficacy and Safety of Cannabinoid-Based Products in Children and Adolescents with Autism Spectrum Disorder, Fragile X Syndrome and Rett Syndrome: A Systematic Review.

This systematic review evaluated the efficacy and safety of cannabinoid-based products (CBPs) in children and adolescents with Autism Spectrum Disorder, Fragile X Syndrome, and Rett Syndrome.

J Child Adolesc PsychopharmacolJun 24, 2026Read summary
Clinical ResearchPsychiatry

Circadian Rhythm Stabilization App to Prevent Mood Episode Recurrence in Patients With Mood Disorders: A Multicenter, Double-Blind, Sham-Controlled, Randomized Clinical Trial.

This multicenter, double-blind, randomized clinical trial evaluated the Circadian Rhythm for Mood (CRM) app's effectiveness in preventing mood episode recurrence in 93 adults with major depressive disorder (MDD) or…

Am J PsychiatryJun 24, 2026Read summary
Clinical ResearchPsychiatry

A Pragmatic SMART Study of Medication and CBT Sequencing in Pediatric Anxiety Disorders: A Randomized Clinical Trial.

This randomized clinical trial evaluated treatment sequencing for pediatric anxiety disorders in 316 youths aged 8-17. It compared initial treatment with fluoxetine or cognitive-behavioral therapy (CBT) and subsequent…

Am J PsychiatryJun 24, 2026Read summary
Clinical ResearchPsychiatry

Sustained pharmacodynamic effects of S-ketamine on cortical excitability and resting-state brain activity: A randomized, placebo-controlled trial.

This randomized, placebo-controlled trial examined the pharmacodynamic effects of S-ketamine on cortical excitability and brain activity in 16 healthy participants.

Br J Clin PharmacolJun 24, 2026Read summary
Clinical ResearchPsychiatry

Efficacy, acceptability, and related outcomes of pharmacological interventions for acute bipolar depression: A systematic review and dose-related network meta-analysis across different age groups.

This systematic review and network meta-analysis evaluated the efficacy and acceptability of pharmacological treatments for acute bipolar depression across various age groups.

J Affect DisordJun 23, 2026Read summary
Clinical ResearchPsychiatry

Duration of untreated psychosis and long-term outcomes: A systematic review examining the critical window hypothesis.

This systematic review evaluated the relationship between duration of untreated psychosis (DUP) and long-term outcomes in approximately 9800 first-episode psychosis patients.

J Psychiatr ResJun 23, 2026Read summary
Clinical ResearchPsychiatry

Dissociable roles of frontal electroencephalography markers in depression: Predictive value of frontal alpha asymmetry and responsive changes in beta power following home-based brain stimulation.

This randomized controlled trial investigated EEG predictors of treatment response to transcranial direct current stimulation (tDCS) in individuals with major depressive disorder.

J Psychiatr ResJun 23, 2026Read summary
Case ReportPsychiatry

Conversion Practices in Eating Disorder Treatment: A Lived Experience Narrative.

Conversion practices (sometimes referred to as 'conversion therapy') refer to interventions that aim to change a person's sexual orientation or gender identity.

J Psychiatr Ment Health NursJun 23, 2026Read case
Clinical ResearchPsychiatry

The Prevalence of Obstructive Sleep Apnoea in Schizophrenia, Bipolar Disorder and Major Depressive Disorder: A Systematic Review With Meta-Analysis.

This systematic review and meta-analysis examined the prevalence of obstructive sleep apnoea (OSA) in individuals with severe mental illnesses (SMIs) including schizophrenia, bipolar disorder, and major depressive…

Acta Psychiatr ScandJun 23, 2026Read summary
Clinical ResearchPsychiatry

Inner speech and the neurobiology of psychosis.

This meta-analysis reviewed neuroimaging studies to explore the relationship between inner speech and psychotic symptoms, particularly in individuals with psychosis.

Neurosci Biobehav RevJun 22, 2026Read summary
Clinical ResearchNeurosurgeryOpen access

Deep brain stimulation of the nucleus accumbens for severe self-injurious behaviour in children: long-term outcomes from a first-in-human pilot trial.

This prospective, single-centre, first-in-human clinical trial assessed bilateral nucleus accumbens deep brain stimulation in six children and adolescents aged 7–14 years with profound autism and treatment-refractory…

Mol PsychiatryJun 22, 2026Read summary
Clinical ResearchPsychiatry

Investigating the effects of antidepressants on measures of insulin resistance in major depressive disorder: A systematic review.

This systematic review evaluated the effects of antidepressants on insulin resistance in individuals with major depressive disorder.

J Affect DisordJun 21, 2026Read summary
Clinical ResearchPsychiatry

Variation in sleep and instability in mood in patients with bipolar disorder and the association between these - an exploratory post hoc study on daily smartphone-based data from two separate randomised controlled trials.

This exploratory post hoc study analyzed daily smartphone-based data from 370 patients with bipolar disorder to investigate the relationship between sleep variation and mood instability.

J Affect DisordJun 19, 2026Read summary
Clinical ResearchPediatrics

Transcranial Alternating Current Stimulation at 40 Hz Improves Social Functioning in Children With Autism Spectrum Disorder: A Randomized Clinical Trial.

This randomized controlled trial investigated the effects of 40-Hz transcranial alternating current stimulation (tACS) on social functioning in 47 children with autism spectrum disorder (ASD).

Biol PsychiatryJun 19, 2026Read summary
Clinical ResearchPsychiatry

Facilitating Thought Progression via a Gamified Mobile Application for Depression: Possible Mediators of Outcomes.

This randomized controlled trial examined the impact of a gamified mobile app based on the Facilitating Thought Progression (FTP) framework on depression and anxiety in 101 adults with mild to moderate depression.

Behav TherJun 19, 2026Read summary
Clinical ResearchPsychiatry

Effects of childhood trauma on executive function, impulsivity, rumination and worry: An umbrella review.

This umbrella review examined the impact of childhood trauma on executive function, impulsivity, and perseverative cognition in a population of 639 unique primary studies.

Neurosci Biobehav RevJun 19, 2026Read summary
Clinical ResearchPsychiatry

Neighborhood Disadvantage as a Moderator of Children's Response to a Dyadic Positive Affect Intervention for Children of Mothers with Depressive Symptoms.

This randomized controlled trial examined the impact of a dyadic positive affect intervention (FPPE) on children of mothers with depressive symptoms, focusing on how neighborhood disadvantage influenced outcomes.

J Child Adolesc PsychopharmacolJun 19, 2026Read summary
Clinical ResearchPsychiatry

Self-administered single-session interventions for mental health in young people: A systematic review and meta-analysis.

This preregistered systematic review and random-effects meta-analysis assessed self-administered single-session interventions (SSIs) for mental health in children and young people.

J Child Psychol PsychiatryJun 19, 2026Read summary
Clinical ResearchPsychiatry

Impact of ICU and post-ICU interventions on the psychological dimensions of patients' PICS: A systematic review with narrative synthesis.

This systematic review examined interventions aimed at improving psychological outcomes in ICU survivors, analyzing 39 studies.

J Crit CareJun 18, 2026Read summary

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