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751 articles

July 202624

Case ReportOncology (Medical)

Anaplastic Thyroid Carcinoma With Kinase Gene Fusions: Report of 3 Cases With Corresponding Cytologic, Histologic, and Molecular Findings.

Three cases of anaplastic thyroid carcinoma (ATC) with kinase gene fusions were analyzed, revealing typical cytologic features such as marked nuclear atypia and sarcomatoid morphology.

Diagn CytopatholJul 18, 2026Read case
Clinical ResearchOphthalmology

Advances in Traditional Chinese Medicine for Diabetic Glaucoma: A Systematic Review From Holistic Pathogenesis to Multi-Target Interventions.

This systematic review examines the role of Traditional Chinese Medicine (TCM) in managing diabetic glaucoma, a complication of diabetes characterized by neurodegeneration.

Med Res RevJul 18, 2026Read summary
Clinical ResearchEndocrinologyOpen access

Relationship between participant-reported outcomes, residual beta cell function and metabolic parameters in youth with newly diagnosed type 1 diabetes.

This randomized controlled trial examined the relationship between participant-reported outcomes (PROMs) and metabolic parameters in youth aged 10-18 with newly diagnosed type 1 diabetes.

DiabetologiaJul 17, 2026Read summary
Clinical ResearchEndocrinology

Protocol for the CLOCKS study: A 4-arm randomized controlled trial testing the independent and combined effects of 2 chronotherapies-early time-restricted eating and daytime bright light therapy-in adults with type 2 diabetes.

The CLOCKS study is a 4-arm randomized controlled trial investigating the effects of early time-restricted eating (eTRE) and daytime bright light therapy (BLT) on glycemic control in 344 adults with type 2 diabetes.

Nutr ResJul 17, 2026Read summary
Clinical ResearchNephrology

Time in Target Range for Hemoglobin A 1c and Systolic Blood Pressure: Association With Adverse Kidney Events.

This observational cohort study analyzed data from 6,542 participants in the ACCORD trial to evaluate the association of time in target range (TTR) for hemoglobin A1c (HbA1c) and systolic blood pressure (SBP) with…

Am J Kidney DisJul 17, 2026Read summary
Clinical ResearchEndocrinologyOpen access

Dapagliflozin does not impair LDL catabolism and induces a shift towards a closer to normal VLDL 1 /VLDL 2 catabolism in individuals with type 2 diabetes: a randomised in vivo kinetic study.

This randomized controlled trial investigated the effects of dapagliflozin on lipid metabolism in 24 individuals with type 2 diabetes.

DiabetologiaJul 17, 2026Read summary
Case ReportMedical Genetics

Long-term clinical trajectory of microvillus inclusion disease associated with STXBP2-related familial hemophagocytic lymphohistiocytosis type 5: A case report.

A 22-year-old male with familial hemophagocytic lymphohistiocytosis type 5 presented with chronic diarrhea that began in infancy and persisted despite bone marrow transplantation.

JPEN J Parenter Enteral NutrJul 17, 2026Read case
Case ReportMedical Genetics

17α-hydroxylase deficiency in a 46,XY individual with a hypoplastic uterus: In vitro functional validation of a CYP17A1 mutation.

17α-hydroxylase deficiency (17-OHD) is a rare autosomal recessive disorder caused by CYP17A1 mutations, and patients with a 46,XY karyotype typically lack a uterus.

GeneJul 16, 2026Read case
Clinical ResearchEndocrinology

Prevalence and cardiometabolic impact of mild autonomous cortisol secretion in primary aldosteronism: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the prevalence of mild autonomous cortisol secretion (MACS) in patients with primary aldosteronism (PA) and its cardiometabolic effects.

J HypertensJul 16, 2026Read summary
Clinical ResearchOncology (Medical)

Pesticide exposure and all health outcomes: An umbrella review of meta-analyses of observational studies.

This umbrella review systematically analyzed 53 meta-analyses of observational studies to evaluate the health outcomes associated with pesticide exposure.

J Hazard MaterJul 16, 2026Read summary
Clinical ResearchEndocrinology

Effects of combined training on glycemic control and lipid profiles in middle-aged and older adults: A three-level meta-analysis of randomized controlled trials.

This meta-analysis of 21 randomized controlled trials involving 1853 participants aged 45 and older assessed the effects of combined training (aerobic plus resistance) on glycemic control and lipid profiles.

MaturitasJul 16, 2026Read summary
Clinical ResearchGeriatrics

Non-pharmacological interventions for older adults with comorbid hypertension and type 2 diabetes: A systematic review of randomized controlled trials.

This systematic review evaluated non-pharmacological interventions for older adults (≥60 years) with comorbid hypertension and type 2 diabetes, analyzing 16 randomized controlled trials.

Geriatr NursJul 16, 2026Read summary
Case ReportEndocrinology

68 Ga-Pentixafor PET/CT as a Noninvasive Alternative in Evaluation of Suspected Aldosterone-producing Adenoma.

A 54-year-old woman with recurrent hypertensive crises was diagnosed with a lipid-rich right adrenal adenoma. Despite inconclusive biochemical tests for pheochromocytoma and primary aldosteronism, 68 Ga-Pentixafor…

Clin Nucl MedJul 16, 2026Read case
Clinical ResearchEndocrinology

Near-infrared autofluorescence parathyroid imaging during total thyroidectomy to reduce the rate of postoperative hypoparathyroidism: A prospective two-center randomized clinical trial with a comprehensive long-term follow-up.

This prospective two-center randomized clinical trial evaluated the impact of near-infrared autofluorescence imaging on postoperative hypoparathyroidism rates in 189 total thyroidectomy patients.

SurgeryJul 16, 2026Read summary
Clinical ResearchEndocrinology

Effect of walking training on blood glucose control and metabolic health in patients with type 2 diabetes: A systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the impact of walking training on blood glucose control in 483 patients with type 2 diabetes.

Exp GerontolJul 15, 2026Read summary
Clinical ResearchEndocrinology

Association of intermuscular and intramuscular fat with insulin resistance, type 2 diabetes, and metabolic syndrome: A systematic review.

This systematic review examined the relationship between intermuscular and intramuscular fat and cardiometabolic risks, including insulin resistance, type 2 diabetes, and metabolic syndrome in adults.

Clin NutrJul 15, 2026Read summary
Clinical ResearchEndocrinology

Immune checkpoint inhibitor-induced type 1 diabetes mellitus: incidence, risk factors, and prognostic implications - a systematic review and meta-analysis.

This systematic review and meta-analysis examined the incidence and risk factors of immune checkpoint inhibitor-induced type 1 diabetes mellitus (ICI-T1DM) in adult cancer patients.

Diabetes Res Clin PractJul 15, 2026Read summary
Clinical ResearchCardiologyOpen access

Exploratory Cardiovascular Risk Modeling of Orforglipron Using the PREVENT Equations Compared with the Pooled Cohort Equations: A Post-Hoc Analysis from a Systematic Review and Meta-analysis.

This post-hoc analysis compared cardiovascular risk reduction projections for orforglipron using the 2013 Pooled Cohort Equations (PCE) and the 2023 AHA PREVENT equations.

High Blood Press Cardiovasc PrevJul 15, 2026Read summary
Clinical ResearchEndocrinologyOpen access

Effects of GLP-1 Receptor Agonists and Dual GIP/GLP-1 Receptor Agonists on Inflammatory and Metabolic Biomarkers in Type 2 Diabetes: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis evaluated the effects of GLP-1 receptor agonists and dual GIP/GLP-1 receptor agonists on inflammatory and metabolic biomarkers in adults with type 2 diabetes mellitus.

Diabetes Obes MetabJul 14, 2026Read summary
Clinical ResearchEndocrinology

Adherence to diabetes self-care behaviors among patients with diabetes mellitus in Pakistan: a systematic review and meta-analysis.

This systematic review and meta-analysis examined adherence to diabetes self-care behaviors among patients in Pakistan, synthesizing data from 65 studies.

Diabetes Res Clin PractJul 14, 2026Read summary
Clinical ResearchEndocrinology

Digital health interventions for diabetes management in the eastern mediterranean region: A systematic review of types and effectiveness.

This systematic review evaluated the effectiveness of digital health interventions for diabetes management in the Eastern Mediterranean Region, analyzing 46 studies primarily from Iran and Saudi Arabia.

Prim Care DiabetesJul 14, 2026Read summary
Clinical ResearchEndocrinology

Non-Glucocorticoid Immunosuppressive Therapy in Post-Glucocorticoid Persistent or Recurrent Primary Autoimmune Hypophysitis: A Systematic Review.

This systematic review evaluated the effectiveness and safety of non-glucocorticoid immunosuppressive therapy (NGIT) in 29 patients with persistent or recurrent primary autoimmune hypophysitis (PAH) following…

Clin Endocrinol (Oxf)Jul 14, 2026Read summary
Clinical ResearchEndocrinology

Physiological-concentration platelet fibrin plasma vs supraphysiological-concentration platelet rich plasma for neuro-ischemic diabetic foot ulcer and other diabetic wounds: A randomized controlled trial.

This single-center, noninferiority randomized controlled trial compared physiological-concentration platelet fibrin plasma (PFP) with supraphysiological-concentration platelet-rich plasma (PRP) during debridement suture…

J Am Acad DermatolJul 14, 2026Read summary
Clinical ResearchEndocrinology

Implementing a novel digital health platform for self-management of postmenopausal osteoporosis: A qualitative study of user experiences, perspectives and implementation outcomes.

This qualitative study explored the experiences of postmenopausal women using a digital voice assistant (DVA) for osteoporosis self-management in a 12-month randomized controlled trial.

BoneJul 13, 2026Read summary

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